For the first layer, I used a few watercolor brushes to setup the scene. I decided to do a black and white image at the beginning because it's a lot easier not to concern the coloring.(Fig.01)
Fig.01
On second layer, I started to draw. It takes me a few hours to finish up the skulls. These was pretty easy though .. hold on, it's quite challenging and exciting.(Fig. 02)
At this point, some additional color were add using the adjustment layers. Now it was time to add some details.(Fig.03 & Fig.04)
By combining different effects and texture brushes, finally "Bleeding Mascara" was finish and here's my final image.(Fig.05)